IF you just want HTML5, I guess go for it.
For me, I like making the game once and then making minor tweaks in C2 to make the most money I can from it. That means exporting to HTML5, Amazon, Android, Windows 8, Windows 8 Phone, iOS, Blackberry 10, Tizen, Kongregate, etc. All with very minor changes to my games I can use all the features that makes the game fit with each system. Some games I make more on iOS and some do better on Droid. Anyway I do it, they make some money on each platform so why not? :)
I just finished my 5th game with Construct 2. All of my games are available on all the systems listed. Sure some you need to pay for dev licenses or whatever, but it pays for itself pretty quickly.