I would recommend either UDK or Unity3D, as they are fairly easy to use as far as managing assets and setting up scenes. You still need some programming skills, though I believe UDK comes with a node-based logic editor (called Kismet I think)... and there is a 3rd party one you can buy for Unity as an addon. And these packages can export to the web, consoles, mobile devices, tablets, and such. Not just the desktop. That is, if you buy a license for that device. And I don't know a lot about UDK, but Unity at least can export to web, Windows, and MacOS in the free version.
Long story short, if you're going to do 3D then use a dedicated 3D package.
Hey. Mind saying which 3D thing you chose, deadeye?
I'm using Unity <img src="smileys/smiley1.gif" border="0" align="middle" />
Ironically, I am using it to make a side-view game that mostly uses sprites <img src="smileys/smiley17.gif" border="0" align="middle" />. Though there are some 3D models mixed in for things that have to rotate and such.