Ashley, I have been having a good look at some other HTML5 games running in Chrome including games made with GameMaker, Stencyl and a few others and they all seem to run absolutely fine. There are no sound issues at all. This can only mean that it is something that Construct 2 is doing.
The effect that I am getting is like someone is pausing the game on and of in rapid succession causing both a jerky frame-rate and stuttering sound effects.
Any ideas as to what may be causing this would be most helpful. This only happens in Chrome but if the problem was Chromes then all of the games would show the same problem wouldn`t they?