I'll chip in my 3 cents since I've been using construct sine construct classic v0.033. For a long while I've been using i5 4200u laptop ( my workstation is far away in another country), and GM games I played seam to perform better. I've played Nuclear Throne and Hyper Light Drifter ( thought this one only work stable 60fps when using external audio interface for sound processing ). My way smaller in scope projects perform much much worse thought, and I do optimise and keep my events as logical as possible. Window size makes a huge difference too. So benchmarks are all good and dandy, but once you start applying logic to the game, it starts falling flat. But point and click games like Deponia should work flawlessly thought, although games like Rayman will most probably lag every now and then unless you wont have that many interactive elements on the layout. But overall it's not that bad, but always creates the feeling that "it's not there yet" and that is always disappointing, sometimes giving you a falls impression that if you will do more then it will certainly be fixed, but it won't , and you will waste a lot of your time. Also, will those jerky frames on the beginning of layout will ever be taken care off by the scirra? Only construct does that.
I know I sound harsh, but this is how it is on my side.