digitalsoapbox I think you don't understand how Spriter works.
Spriter is almost-frameless animation editor can save JSON or XML data in export to manipulate position, scale, frame, etc. when it's exported, sprite sheet is small and simple because it has 5 parts of graphic thanks to C2 editor, BUT depending on the video game design.
If we use rendered frames by 3D like rotating cube in isometric in Spriter, it doesn't make sense.
There an interesing point about different angles in sprite sheet could reduce size thanks to Tangram logic, we will see what happens.