For the sake of building their projects, big companies with their vast resources can always just build their own Construct.
Let's look at UbiArt by Ubisoft.
In Youtube videos they show how Rayman was built with it.
What special you can do there,
Add 3D objects (All or most bosses in Rayman. Maybe can be done in Construct with Q3D)
Make use of middleware engines like PhysX (look for Cloth-like physics on Water. We have Box2D and can find alternative on the forum. Also you can create some cool things with WebGL effects)
Create bone animations (All 2D animations in Rayman. We have Spriter for this, but yeah...I would really love to have it inside like in Construct Classic)
No wonder Ashley once used Rayman as example to talk about optimization