I agree with the fact that file size at the end matters little.
Personally, my only complaint with NW.js is the fact that at multiple times had issues like lag, fps drops and now debugger not working (bug report can be found in the bug report section done by another user).
Please correct me here if I'm wrong but since there's a store, maybe someone could make a new exporter for C2?. Personally I'm ready to pay for an exporter tailored for bigger pc games since the few issues with NW.js slow me down.
Personally, I feel its a shame for C2 to limit itself to just mobile devs (maybe I'm wrong).
Cheers!