Ok. I have found the problem, but not a solution. It's the system| layout scale 0.6 that causes the offsetting...
I must say that I was almost ready to bite my monitor when I realized that I should check the scale factor...
If you set the layout scale to 1, it works ok. I don't know how to overcome this, I tried the magicCam plugin to see if the scaling from within the plugin uses an other algorithm, but it renders the same results.
That's why I insist that a real 3d work space is crucial. As it is now, C2 scales everything from 0,0 coordinates, this is causing the offset. Perhaps there is a way around this by using the parallax values of the layers and ass/subtract some offset in relation to the scale, but this is too complicate for me.
Some hero