Projects in C2 easily get overcrowded with events and messy when it comes to larger projects. You'd need very good management skills i.m.o. C2 also lacks certain systems which would be really useful in an old-school RPG like tile-based map editors.
In a maker made specifically for RPG development, you'd have a whole menu dedicated to creating items and one for skills, all easy UIs which manage a very common aspect of RPG already there for you.
You'd have a lot of advantage in the non-standard RPG features like say if you were to implement a physics element into your RPG.