All sprites when put on the layout rotate automatically to 0 degrees unless you change that in the sprite settings.
0 degrees is facing right, down is 90, left is 180 and up is 270 with all degrees between 0 and 360 covered.
First you need to rotate the sprite in the editor so it is facing the direction you want it to start at and set that in the sprite settings.
Then in the events you can rotate the sprite Using Rotate Towards position and set that to the X and Y of the position or object you want it to rotate towards.