I know this is a very old post, but I wasn't able to find many other posts talking about this.
Does anyone have have any tips or techniques to reduce this effect? I've been working on a fast paced arcade game for awhile now. I've finally added in the graphics, and I notice how blurry everything gets when it moves. It makes the art very unreadable, and tends to give me a headache when looking at it for too long. I realize some of the above posts said this was an LCD issue and not a Construct 2 issue. But I've never really noticed this effect in any other 2d game I've played, but in Construct 2 and Construct Classic it is very apparent.
Can confirm, am also having this issue and is glaringly obvious. Running at 60fps if that information matters. Messed with all the configuration settings but no changes. Letterbox scale, letterbox integer scale, no results.