I answered this when another asked a question.
The answer is yes it can be done.
The thing is. Game creation with an open tool like C2 isn't about "can C2 create Y game". It's about can you make the game with all the tools. C2 has a wonderful number of tools that you can make ANY 2d game. It has fantastic tools to make a platformer in minutes. But outside of platformer, top down, and some in the samples. Your going to need to put in a little more work.
I managed to create a P&C demo in 10 minutes. After 4 hours I had
scene changes
scaling with the scene
item pick up
inventory
positional and distance audio sounds
however like any game moving prototype to a polished product is entirly a different story.
Check out The Blue Code. It is a demo Point & Click adventure game done in C2. This is the facebook page.