It is very much feasible. You will just need to form your data structures appropriately.
You want to make it such that you can input quizzes by XML or JSON (I am partial for JSON, myself), then you can just input new JSON into the server each week. Like:
{
"quiz":
{
"questions":[
{
"questionId":1
"question":"What color is the sky?",
"answerKeyWords":["blue"],
},
{
"questionId":2
"question":"Choose the image that matches the Eiffel Tower?",
"answers":["../images/TajMahal.jpg","../images/AngorWat.jpg","../images/EiffelTower.jpg"],
},
{
"questionId":3
"question":"Name three countries on Europe.",
"answerkeyWords":["Germany","France",'United Kingdom","Belgium","Holland","Poland","Austria","Italy","Spain","Portugal","Montenegro","Moldova"],
}
}
}
Then you can do a comparison or contains character search to see if their input answer matches any of the key words.