DalekAddison
if you are speaking from the aesthetic side of thing, i think you should aim for visual style instead of the graphic side, since like Kyatric said construct is a 2D engine and all the graphic stuff will be sprites and bitmaps; unless you are just curious about design stuff... either way here is my 2 cents:
visual style: aesthetic, feel, impact, perception, mood...
graphic: number of poligons that can be draw on screen, number of particles/screen, size of the image file so more detail can be put on the texture...
if visually speaking you can "say" a lot more with low poly than pre-rendered graphics, then you should go for low-poly; i think the important thing is to make it on a way that your game could be played for ages without the feel it is dated. Ex: zelda wind waker, okami, jet set radio, katamari series, odin sphere, valkyrie profile