I've never used directional conditions, but it seems straightforward enough:
> + System: On start of layout
-> PF_Map: Begin adding directional conditions at 2,1
-> PF_Map: Add direction LEFT
-> PF_Map: End adding directional condition for the current tile
This way the tile at (2,1) can only be entered from the left.
I nearly tagged you in this as I knew you'd come up with a quick obvious answer as I've seen you in other threads using this plugin.
Works a treat thanks man.