Performance Question - For Loop or Picking

As an example situation:

Sometimes I use actions on objects that are pinned to other objects, and I've found two working methods:
• Use a for loop and perform the action on the condition that the pinnedUID property is equal to the pinned object's UID
• Use the Pick By Comparison to see if pinnedUID property is equal to the pinned object's UID

I've found the Pick events to be useful for a lot of situations like them, but I'm curious to know if these have much, if not any negative effect on performance.

Optimisation: don't waste your time

Optimisation: don't waste your time

If you saw the project files I'm using, optimization is pretty hard to ignore.