Keep in mind that most of the 'is it possible in Construct' questions are less 'is it possible' and more 'are you capable of doing it'.
Agree with Excal,
You are talking about a goodly amount of text. I assume you mean using a lot of text in your game. This shouldn't be any problem.
If your sprites or spritefont look good in Photoshop but bad in a C2 game it could have a number of reasons.
- Scaling within C2 (If an object is bigger onscreen than the original sprite it will have to be scaled up and this will change it's crisp appearance)
- Objects not being at precise coordinates ( if your object is at x(100.3) and y(75.6) instead of 100 and 75 the program has to calculate it's appearance, while moving this shouldn't be a problem, but static objects sometimes lose their crisp appearance.
Sometimes changing the pixel-rounding and/or sampling settings in the project properties is enough to help with this, but it can also create unwanted effects.
Also the type of scaling in project properties offers possibilities to keep your game looking crisp.