I've yet to try Windows 8, but I know that IE10 doesn't support the Web Audio API yet. Perhaps that's your problem and you need to repack those sound files (you're probably using ogg, I'd imagine) to some other format.
Since IE10 supports neither Ogg Opus nor Ogg Vorbis and Construct2 doesn't support MP3 (for obvious reasons. Namely, asenine licensing fees), this leaves you with AAC. i,
When I imported WAV music/sound effects
"Construct 2" converted them to OGG and M4A files.
So there is no way to get audio working on IE10?
That sucks!
JeZ+Lee