if we want change sprite shape ，we only change width ， height， scale，if we can use mesh change sprite shape，and set each frame for each mesh shape， we will make Very beautiful animation！
send me your project. i will try to help you
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mesh can help us make smile speak animation so easy .we don.t need anima2d on u3d. Sprite plugin is most used in c2 ' if add mesh for it. all c2 game can make new animation for their Spritep