Are you asking how to make animations sprites, or how to use the Sprite object in C2 in order to have an animation displaying ?
If the first, you should have a search in the "Tools/ressources" forum where the question has been treated through many tools and links to tutorials.
If the second, have a look at this tutorial which quickly covers the setting of an animation in C2 and have a look at the manual entry which provide more informations about the interface.