THe only thing with frames are animations for your sprites. The sprite object has properties for animations that you can access in your event sheet, you can set the animation to a particular frame, start a particular animation if you have more than one animation for your sprite, etc...
Your level/layout doesn't have frames, just objects that follow behaviors. Each object can have animations as stated above. You can create a button easily by creating an object, and creating a click event for it.
You can also use the layouts restart action to restart the whole layout as well.