Um. 2D? Top down? Side scrolling? What gameplay does your game feature? Those questions are more important than "can (some vague game idea) be done in C2?".
I'm guessing top-down exploration game with seamless environment. The seamless transitions can be tricky if you are not familiar with the concept, so you may want to research it a bit, experiment in the C2 sandbox. Terrain generation, etc. is another fairly complex concept.
But that is true regardless of the game engine. In any case you are going to need some game development experience under your thumb.
Start small, with prototypes testing each of game concepts separately. One prototype for inventory system, one for crafting, one for seamless transitioning etc.