Searched but couldn't find this problem being reported, closest I could find related to the game pausing when tab is not active on screen.
The problem doesn't happen all of the time but sometimes my game will freeze when I have it open in a tab and drag the tab to the taskbar so that it opens free of the rest of my browser. Not 100% the game freezes so much as the mouse becomes nonresponsive and there doesn't seem to be any common theme for when this does or doesn't happen.
I thought it was just happening to me but it was the first bug report I got when I launched the game on Kongregate-
https://www.kongregate.com/games/fatesjoke03/american-villainy.
Any ideas?