First. Thank you for sharing your information .
First of all, poor game performance is not always the issue of HD graphics, often unoptimized code (events) are the cause of performance leaks on low-end devices.
Possibly and Commonly true but not in my case when I tested a simple 1280*720 in a jellybean (4.1.2 Android device) Seams were seen like 3 pixels border for each sprite and tile and 3~10 fps. My only event on that spritesheet was to move the scroll x with lerp to make a scenematic view. The phone I used only supports (640px*360px) for playback, I don't know if it is the playback resolution limit is the fault or the optimization. There are only 3 phones I used to test 1280px*720px resolution games. 1 is Kitkat(4.4) (HD screen resolution) and another 1 is Lolipop(5.1) (HD screen resolution) and the other 1 is the Jellybean (4.1.2) (640x360 res).
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I made a performance report I got from testing, I have only 3 devices which I tested on.
Feel free to correct or add details for my accuracy is based on estimate.
*4.4 Kitkat (Supports HD)
Only Graphics and Simple Events: A little fast
With Graphics and Game Events(Finished Game) : Playable and a little fast or acceptable for me.
*5.1 Lollipop (Supports HD)
Only Graphics and Simple Events: Fast (but small "seams" appear - must be graphic card limitation, I don't know the problem and I am still looking for answers)
With Graphics and Game Events(Finished Game) : Faster than Kitkat or Smooth Play (with small seams) - I also set Pixel rounding "On" to remove it but on "lerp + Layout scale" it shows the seams again.
*4.3 (Feedback of my game)
Only Graphics and Simple Events: I don't know yet.
With Graphics and Game Events(Finished Game) : Playable but a bit laggy.
4.1.2 (640x360 screen resolution)
Only Graphics and Simple Events(platform behavior and solids): Bad quality and very lag (playable but very lag). I don't recall but I think there were seams. Not sure.
With Graphics and Game Events(Finished Game) : Certainly not playable even on splashscreen. Very Lag and looks like there is a 3px sized seams.