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I pointed out the mobile games just to show successful games are made with Construct 2. But if your asking can Construct 2 make games that are successful on PC , then yes of course but its up to you the creator to make one.
But also like I said if you want to succeed you need a marketing budget to effectively get your game out. Most developers just make games and release them with free marketing. If you do that then its going to be tough to get sales. You can try and maybe be lucky or you can invest in the game to help it reach a fanbase.
Mortar Melon is the only PC game that reached 1 million downloads and that was back when Windows 8 was popular. Thats the only PC success story I know of.