Ashley : the n°1 could be an improvement upon the current system if it can be done swiftly. Some "reload all animation" button or right-click option in the anim view could be nice. This still doesn't solve the tedious work of re-importing many background elements though. Can't compare with bigger engines or ask for a complete take over the system, but I feel like a lot of time is wasted arranging, creating and reloading objects from within c2, rather than using the windows explorer directly (cf. Unity's project manager).
To list things more clearly, I'd see some design like that:
1- a folder structure in project mode that mimics the explorer view. Only sprites with multiple frames and/or animations are stored inside a sub-folder using their c2 name
2- C2 automatically detects changes in the folder structure or files in the project view based on changes done from the windows explorer -> updates the files and folder structure inside the C2 editor.
Dunno whether it's feasible, but I think it conveys the idea. Something that permits a professional artist to drag and drop his 30 background sprites freshly exported using generator in photoshop, overwrite the current construct2 files, and voilà: the whole environment is updated in construct. That's basically how Unity (and game maker I believe?) handles assets.