I mean , the developers construct 2. Because a mouse is connected via plug-in construct 2.
It just isn't possible..
Games exported from Construct2 are html5/javascript-based and run in a browser-environment..
Javascript can't get control over the cursor/mouse..
These settings are handled by the operating system to which you can't get control from the browser..
You could ask the browser creators to make hijacking computers easier by giving websites acces to system settings, but I don't think they'll see benefits..
You can hardly blame the Construct2 developers for not giving acces to something that isn't accesible..