Just my 2 cents, C2 is an engine, chosing an engine/language/platform/etc is part of thz job I think, however, popularity of said engine should not come into play, except for support(a large community wih helpful member will help more easily than a little community in general), what the engine does, how it does it, all comes into play, in general it is not a matter of "did C2 did somehing great", but more "does C2suits me and my plans?".
C2 is an html5 engine (html5 being multiplatform and more and more performant as time passes, that also has the advantage of not being an executable file), however it is not as powerful as native (when performances is a real concern, that comes into play), wrappers are not to enter into consideration as a part of C2, they are more a part of html5 (and they become more and more useless technically speaking as time passes, being more a psychological executable file, since html5 is not yet a good market except for publishing, and even then, it is more driven by profit and insane requirement more than something viable long term wise).