the sample I posted does create the mesh at runtime.
In event 3, the second action - Cloth -> set mesh
it then goes on to create a dot over each mesh point. I used ROJOhound's code to create the dots. Take a look at the "Mesh distortion" sample project on C3's start page for an alternative way to create the points using lerp.
If you mean create the mesh points in some random location, then no. You have to create a grid of dots over the whole image, in as many rows and columns you want. Once the mesh points are created you can move any point, but that will then distort the image.