Yep<img src="smileys/smiley2.gif" border="0" align="middle" /> but I would suggest giving users a choice on whether or not to run the app on startup. What I've done here is opened components.iss in the examples folder and modified it slightly; I've highlighted any changes... hope it helps.
[Setup]
<font color="blue">PrivilegesRequired=admin</font>
AppName=My Program
AppVersion=1.5
DefaultDirName={pf}\My Program
DefaultGroupName=My Program
UninstallDisplayIcon={app}\MyProg.exe
OutputDir=userdocs:Inno Setup Examples Output
[Types]
Name: "full"; Description: "Full installation"
Name: "compact"; Description: "Compact installation"
Name: "custom"; Description: "Custom installation"; Flags: iscustom
[Components]
Name: "program"; Description: "Program Files"; Types: full compact custom; Flags: fixed
Name: <font color="blue">"autorun"</font>; Description: "Help File"; Types: full
Name: "readme"; Description: "Readme File"; Types: full
Name: "readme\en"; Description: "English"; Flags: exclusive
Name: "readme\de"; Description: "German"; Flags: exclusive
[Files]
Source: "MyProg.exe"; DestDir: "{app}"; Components: program
Source: "MyProg.chm"; DestDir: "{app}"; Components: <font color="blue">program</font>
Source: "Readme.txt"; DestDir: "{app}"; Components: readme\en; Flags: isreadme
Source: "Readme-German.txt"; DestName: "Liesmich.txt"; DestDir: "{app}"; Components: readme\de; Flags: isreadme
[Icons]
Name: "{group}\My Program"; Filename: "{app}\MyProg.exe"
[Registry]<font color="blue">
Root: HKCU; Subkey: "SOFTWARE\Microsoft\Windows\CurrentVersion\Run"; ValueType: string; ValueName: "MyProg"; ValueData: """{app}\MyProg.exe"""; Components: autorun; Flags: uninsdeletevalue</font>