I can report that I have the same problem on my P4 with an Intel GPU, PS 2.0, 128mb vram. Whenever I increase layout width/height beyond 2048 I get the error, and it remains even if I revert everything to normal. Only way is to restart construct.
I have not much in my scene, a tiling 256x256 texture, a player sprite and a 50x50 distort .mesh.
I can add that when zooming out more than 50% the error occurs even when on 2048 res. Well, guess you can never trust built in GPUs to handle anything at all.