This is a rather chunky request, but whatever.
I like Construct's interface (even if it's a derivitave of Clickteam's software interfaces) and I think it would be great to be able to use it for cross platform development of SNES/Genesis era-style games. That is 320x240 max resolution, tilemaps and the like. Still with a Python backend but with a more generalized software renderer capable of running on multiple platforms (even low spec stuff like GP2X, Dingoo, some mobile phones).
It would basically require a fork, but I think it would be incredibly useful since it's still a niche that is yet to be exploited.