It depends: Touch with mouse input enabled can work if all you need are left button clicks and drags. If you want something like detecting the mouse cursor hovering over an object, you still need the Mouse object for that, as the concept of hovering doesn't apply to touch input, or if you want to make use of middle/right clicks or the mouse wheel.
Thanks. I have am making a Clicking Game (what I have so far here) and use mouse for things like hovering, but I have a text button that when you click on it, it goes to different layouts. I was wondering if I needed to use mouse and touch for it to work, but you answered my question! Thanks a million!