I wonder if this is a RAM issue. How much RAM does your computer have, and what GPU do you use?
Do you use a gaming laptop? If so, perhaps the browsers you use are not using the dedicated GPU. This might be fixable with the nvidia/whatever software you use to configure your GPU, but in my case, I had to disable switchable graphics in my bios or something (this was years ago so I don't remember exactly what I did).
I assume you have very busy layouts with many sprites and such placed everywhere? Could you try opening your project, then open a "smaller" layout that has less objects within? Does it crash?
Can you open Kiwi Story or some of the example projects in C3, and see if it crashes?
I know it sucks to be forced to use a browser when you've been happily using NWJS all this time, but I'm hoping you will find the cause to this problem, and I hope it's a smooth experience beyond this. I used to use C3 in NWJS ages ago, but I had so many terrible problems, such as NWJS unpredictably silently closing, without allowing me to save, even on a fresh install of Windows 10. I now use Chrome to run C3 (I don't use Chrome for anything else except C3) and I use remote preview, along with the remote preview tool, to test in NWJS. And I got to say, using Chrome has been the MOST stable C3 experience I've had so far - I wish hadn't faffed around with C3 in NWJS for so long. The only slowdown I get is when I have long event sheets with many sub-events and groups expanded, but I just collapse everything and it speeds up again. I don't really use layouts for my current project though, so I don't have any "busy" layouts to test if it crashes for me, other than my object repository layout, which is a bit slow, but no crashes.