> Periodically all data in construct is erasing, which means installing all plugins, doing setup, searching for recent files from scratch
Check if any of your browser settings periodically delete data, or if you have any browser extensions that would do that. Commonly privacy-focused extensions will clear all data ostensibly for privacy reasons, but that will also wipe all data saved in Construct. Further they may refer to this data as "cookies", which is an unfortunate term which I don't think makes it clear this will happen.
If something tried to clear data while Construct was also accessing storage, you may see write errors like the one you showed.
The reason is simple actually, I had less than 10% on the C disk
I didn't touch anything in chrome, everything by default, no specific extensions that can affect