Zebbi The IDE GUI is much more modern feeling in version 5 - version 4 is still good, though - not like AGS at all.
Bleenx: yes, Visionaire is for 2D and 2.5D adventures. I use Spine animations, which work well - but no blending between animations is supported, unfortunately.
I checked into Unity Adventure Creator, and I discovered it even supports Dialog System with import of Articy:Draft files. That is pretty cool. I will have to test it to see how well that works.
I do think Visionaire's workflow is much friendlier for 2D point and click adventures.