Check if a specific sprite is visually obstructed on the point where it's being clicked?

I have the following use case:

• Lots of different object types are on-screen (e.g. sprites, 9-patch etc.) and moving around.
• These moving objects will be randomly changing in z-depth.
• Changing these object types in order to achieve a solution is not a possibility.
• The objects and object types are many, meaning that adding them to families in order to run any checks would be cumbersome (but possible if it's the only viable solution).
• I need to check if true, only when the player clicks on a specific sprite (i.e. I only need to run the check for this specific object) when it's not obstructed by another object.

Or to put it in more simple terms:

How can I check when a specific sprite object is not visually obstructed by any other visible object, at the exact point where the player is clicking on it?

Obstructed meaning what?