Dang, this looks amazing!
Question, is the entire game map one giant layout with transitions and x/y teleports or is it smaller different layouts, linked via events?
Also, are you using individual sprites for each of the map tiles or a tilemap?
Great questions - although you're able to use one big layout, I'm using multiple rooms. At this point it's just easier for me with the engine I've built. For the map elements, I do build them in Tiled first but actually convert the maps into arrays, and the final maps are generated from that array using corresponding sprites.