When you use the 'reset layout' command, it doesn't re-set the global variables.
Add a Global variable called 'wipesave', and let it be 0 by default.
When the player clicks the 'New Game' button, set 'wipesave' to 1.
Add a condition on the start of the layout:
wipesave=1
Save game
Here you might want to also use 'Reset Global Variables'
That should do the trick!