Sounds complicated. Seems like the global layer seems to be the approach though. Then just update on layout switch. I can't really think of any other way to have an inactive layout being modified, unless it's all happening in an array by numbers, and somehow transfer the whole array from one layout to another.
That's essentially what I'm doing now using nested dictionaries (then saving a JSON file with NWjs)... transferring data between each layout... but it's about to get a whoooole lot more complicated xD
I think I'm going to have to make some "ghost objects" on my main layout that will dummy as data-clones to my second layout. This way I will have a few invisible objects that I can store the same instance variables and positioning data in, then save and load that onto the map; almost like a reverse mini-map.
I'm still not sure how to handle tile based "random events" though if the tile data isn't directly accessible without changing layouts. I'm not sure that I could really go with using a "map layer" and just turning it on and off, because of the sheer amount of objects between my main "game layout" and the map - it would implode something I think. ARGH!
*EDIT*
Bugger it, I'm going to try and merge the layouts using a global layer and just if if catches on fire or not - there's only one way to find out right?
~Sol