Ok.. so something like global layers?
I've never worked with RPG Maker or MMF2, but all of these programs have their own seperate ways of achieving the same thing..
Instead of talking about layouts and not layers and such and comparing it to other programs, you might get a better response on how to create the effect you want using Construct2 by telling exactly what effect you want..
You could for example create global layers, use groups (in included event sheets?) to activate/deactivate the events related to them.
This way you could create your menu in a seperate layout and have it displayed over (in) any other layout.
But as it's unclear to me what you want to do exactly and why you want to do it a certain way, I might be way off in my explanation..