I don't think there are any different really. 50 images are 50 images. You could probably argue that making 50 individually images would have a bigger impact since it would have to take the objects into account, but I think that would be such a little impact that it would be a lot more efficient to just reduce the image size by 1 pixel.
Anyway not 100% sure, its just what I think
[quote:2o9onqn3]Then when overlap occures i compare the animation frames of the one on the background and the one dragged over. Is that the way to go?
Yeah that should work fine.