Edit: I just tried exporting the game to Node-Webkit. PNGcrush and PNGout crashes instantly. Is there a chance my image files have gotten corrupt somehow?
If that would be the case I guess your capx wouldn't open.
Perhaps if you posted it for us to confirm or see if there is a configuration issue.
To be sure, check out the several project's properties and perhaps try to modify some.
On the other hand, you might want to check for errors in browser (although this does require a tab to open) or troubleshoot C2's preview server (even though the issue should also apply to other projects as well).
Last thing, if you have configured to be [url=https://www.scirra.com/tutorials/247/how-to-preview-on-a-local-networkpreviewing over LAN/WI-FI and are not executing C2 as an admin, there will be a dialog displaying when previewing that will tell you "Unable to start HTTP server".
Clicking "OK" executes preview on a normal basis.
Nevertheless from time to time this dialog instead of appearing on top of all windows UI will simply appear in the background and the preview won't happen before you've clicked OK.
This might be something worth to check out too.
Here are clues to investigate.