It depends on the effect you are after.... Spriter permits blending between different animations and give a smoother animation effect than sprite sheets can (in most situations), so the final animation appears of a high standard but uses up only a small amount of memory. However, Spriter has a performance overhead - you can't have a large number of Spriter objects running even on desktop without performance being impacted. There is also an instantiate time for Spriter objects, so that they might appear up to a second after the layout starts (work arounds are possible, though, by delaying fade-in etc). The best thing to do is give Spriter a try and see if you like what it can do.