Making a quick assumption - You're positioning your sprite at 0, 0 and you see part of it off the layout. By default, the center of the sprite is the origin point, so you are moving the center of the sprite to 0, 0.
To move it to the top left, go into the sprite editor and change the "origin" imagepoint to 0,0.
If that't not it, a screenshot or capx might describe your problem more clearly.