I've been think about this a bit lately.
It seems like C2 is becoming pretty mature now. Most of the extant limitations are to do with the IDE, which seems unlikely to change much until C3.
With the IDE on the back-burner, what I'd like to see is the incorporation of important third party addons (behaviors, plugins, effects) as official. Much like what happened with the 'Function' plugin, which was a game changer for C2.
The first thing that comes to mind is Paster/Canvas. It's mind-boggling what can be done with it, and it would be an invaluable addition to the native C2 toolkit.
LiteTween is another time saving behavior that should be in C2 by default. It's simpler and more intuitive than mucking around with lerp/qarp/cubic, and as it's mostly just value manipulation, it would be unlikely to break very often.
There are many more great plugins, but those would be my top two.
Yours?