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It all depends on how you lay out your project.
I have a team right now, who are working on a serious project using CC, and feasibly this thing might be a little unworldly. We already have 3D projected entities using 2D objects, and a 3D "point cloud" system. The game assets are going to be in the hundreds of Mb, if not even in the Gb by the time we get there...
You have to "modularize" your project. Make sure your assets are not embedded in the EXE itself, rather kept externally (encrypted or not, your choice). Make sure you are using methods for optimising what assests are loaded into memory, and when. All of these things can help make a game really any size you want... you just have to be clever with the way you splice everything together. I have even seen people make a game using several EXE's... which one EXE can quit itself and load another.
Clever boys and girls can make the best anything ;)
~Sol