I have been using Construsct for a bit over a month now, only during weekends, so you can consider me more like a n00b than an advanced user.
My goal is to make a point and click game too and this is what I got so far
This is only a proof of concept, the guybrush sprite is only temporary of course and there is still a lot missing but I already got some cool features implemented, including menus, pause, collisions, Z sorting, depth, lighting, being able to control the game with mouse, keyboard or controller seamlessly, dynamic screen loading ( I have one single layout for all screens, the data are loaded from an xml file). All this was made only working on sundays of the last three weeks pretty much. Did not even have to ask for help, just reading the doc and searching this forum.
I know there are tools like Adventure Game Maker which are pretty much dedicated to making point and click game but I liked the idea of making a game in HTML5.
So yeah, it can be done and that's what I'm aiming at. I actually think the harder part will be to write a good story and design good puzzles, than making the game work